Dr.
Larry Carpenter, DVM MS
Diplomate,
American College of Veterinary Surgeons
Veterinary
Surgical Services
FAQs
about Disk Disease in Dogs
1.
What and where is the disk?
The
disk is made up of fibrous connective tissue and serves as a kind of spacer
between vertebrae in the backbone. The disk lies underneath the spinal
cord. The disk is like a jelly donut – with a soft inner part and a
tougher outer part:
a) The
nucleus pulposus of the disk is in the center and acts as a deformable tissue
that is much like a shock absorber for the spinal column.
b) The
annulus fibrosis of the disk is a tough fibrous outer layer that holds the
jelly-like nucleus in place.
2.
My doctor says my dog has disk disease, why is this happening to my dog?
Your
dog very likely has a genetic trait that leads to early degeneration of the
disk. This is especially true of small breed dogs that are classified as
chondrodystrophic.
3.
What is disk degeneration?
In
most dogs and people, the jelly-like inner core of the disk gradually
dehydrates with age and becomes less deformable so that it no longer acts as a
cushion. This usually happens late in life for most large breed dogs, but
in some small breeds (Dachshunds for example) disk degeneration occurs rapidly;
usually before the dog is 2 years old.
4.
What happens when a disk herniates?
The
mineralized core of the disk is unable to deform with the movements of the dog
and is forced upwards through the tough fibrous outer layer of the disk and
into the spinal canal. This material takes up space in the spinal canal
and squeezes the spinal cord against the boney interior walls of the canal.
This pressure on the spinal cord results in pain and weakness or
paralysis. The neurological condition caused by disk herniation is
variable depending to a large extent on how much of the nuclear core is pushed
against the spinal cord and also on how forcefully the material strikes the
cord. Onset can be rapid – within minutes of a jump or a fall that initiates
herniation – or it may be slower- over a period of hours to days. The
condition is called Intervertebral Disk Disease of IVDD for short.
5.
What breeds of dogs are most likely to be affected by disk disease?
Dogs
that are most susceptible to IVDD are classified as chondrodystrophic breeds.
Chondrodystrophy is a kind of dwarfism. Dachshunds are by far the
most susceptible breed; in fact, they have a 10-12 times higher risk for disk
herniation than all other small breeds combined. Beagles, Poodles, Shi
Tzu’s, Pekingese, Bassets and Welsh Corgis are among the other breeds of dogs
that routinely get disk disease. The truth is that individual dogs of
almost any breed can have this type of problem if the right circumstances are
present.
6.
Can my dog die from disk disease?
In a
low percentage of cases the damage caused by the disk herniation can lead to
uncontrollable deterioration of the spinal cord in both directions from the
site of the herniated disk. This deterioration leads to paralysis of all
four limbs and ultimately affects vital functions such as breathing which leads
to death. This condition is known as Progressive Myelomalacia.
7.
How is disk disease diagnosed?
Your
doctor will do a neurological examination which usually demonstrates pain and
loss of function caused by disk herniation. The exam will also help to
localize the problem to a general area or region of the spinal cord. We
grade the loss of function resulting from disk herniation in the lower back in
order to etermine what the prognosis of recovery is and what therapy is most
appropriate. We use the following scale:
Grade 1 – Pain
Grade 2 – Weak but able
to walk
Grade 3 – Weak, unable
to walk
Grade 4 – Paralysis
(usually accompanied by loss of bladder function)
Grade 5 – Complete loss
of feeling
8.
How is disk disease treated?
Mild
cases in dogs that have pain only and minimal loss of function (Grade 1 or
early Grade 2) are usually treated with strict cage rest and pain relieving
drugs. More serious problems such as extreme weakness or paralysis of the rear
legs usually require surgery. Complete loss of feeling is considered an
emergency and surgery should be done as soon as possible (but certainly within
24 hours) to allow any chance of recovering the ability to walk.
9.
How is the specific location of the herniated disk found?
Special
x-ray techniques are needed to highlight the area of the spinal column where
the disk has herniated. Survey x-rays are usually done of the area of the
back where the neurologic exam indicates a problem. When we are planning
to do surgery, we need to know the exact location of the herniated disk.
A procedure called a myelogram is the most common way to locate the
herniated disk. A myelogram is a done with the dog under a general
anesthetic. A spinal tap is done and a dye is injected into the space
where fluid circulates around the spinal cord. Once the dye is in place,
several x-rays are taken. When a herniated disk is present, the location can be
determined because the disk material takes up all of the space around the
spinal cord and pushes the dye away. The spinal cord segments where the
disk has herniated are characterized by a lack of dye, seen on the x-ray as a
gap or gaps in the white dye columns surrounding the vertebral segment(s) where
the disk has come to lie. The disk and hemorrhage and swelling are
keeping the dye from surrounding that particular part of the spinal cord.
CT
scans can also be used. A CT scan shows that most of the spinal cord is
surrounded by a thin layer of fat that is less dense than the spinal cord
itself. The mineralized disk material can be seen on the CT scan because
it is more dense than the epidural fat. The CT scan shows “slices” of the
spinal cord and can pinpoint the location of the disk herniation. A CT
scan can be arranged by scheduling with a scanner in Rapid City.
Scheduling usually requires some lead time and it is not possible to
complete a CT scan as an emergency procedure.
MRI is
considered the “gold standard” for imaging degenerative and herniated disks in
the spinal canals of humans and animals. We do not have access to an MRI
machine for animals in the Black Hills area. MRI for animals is becoming
more common and most veterinary schools and large metropolitan veterinary
practices have MRIs. There are several MRIs for animals in the Denver
area. MRI and CT are noninvasive and hold little likelihood of causing harm.
So when they are available they may be preferable to a myelogram.
10.
What is done during surgery to correct the problem caused by disk herniation?
Once
the specific location of the herniated disk has been determined, the surgeon
uses specialized equipment to remove the bone that forms the roof over the
spinal cord to help relieve the compression. The disk material then must
be removed from around or under the spinal cord with small sturdy instruments.
The nearby disks are usually also fenestrated – that is – the surgeon
cuts the outer layer away from the nearby disks and removes the inner core so
that it cannot be pushed up into the spinal canal at some future date.
11.
What is the prognosis for recovery from disk disease?
The
prognosis for recovery is related to the degree of damage that the herniated
disk has caused to the spinal cord. For example, dogs that are Grade 1 or
2 have a good prognosis for recovery when either medical or surgical therapy is
used. Dogs that are Grade 3 or 4 usually do much better with surgical
treatment. Some dogs that have been paralyzed will have some weakness
that remains even after recovery is complete. Dogs that have a very rapid
onset of paralysis may have a somewhat poorer prognosis than those with a
slower onset of symptoms. Even with prompt surgery, dogs that have lost
all feeling (Grade 5) have a 50% or less chance of recovering the ability to
walk and control urination.
12.
How important is confinement to the success of conservative therapy for
thoracolumbar IVDD?
Strict
confinement is crucial and is considered the cornerstone of conservative
therapy for IVDD (the dog is kept in the cage at all times and only taken
outside to relieve him/herself). In order to accomplish the goals of
preventing further extrusion of the nucleus of the disk and to promote healing
of the outer layers (the annulus) of the disk, strict confinement is necessary.
Activity can easily push more of the nucleus into the spinal canal and
dramatically worsen the neurological status. It is not uncommon to see
dogs that have “gone down” after a short course of pain relievers given without
insuring that the owner would enforce strict cage rest. A typical IVDD
case requires up to 6 weeks of confinement. This time frame is based on
the time it takes the annulus to heal by scar formation. Fibrous
scar tissue takes 3 weeks to begin to be laid down and scar formation
reaches its peak at 6 weeks. So strict cage rest is followed for the
initial 3 weeks. After a recheck exam that shows improvement, slightly
more freedom is granted. At 4 weeks more freedom is allowed if the
recheck exam shows substantial improvement. After 6 weeks have passed,
healing should be well underway and the recheck exam should show a more nearly
normal neurologic status. Then cage rest can be discontinued, but
lifestyle changes designed to help prevent a recurrence should be
followed – that is weight control, limited stairs and jumping.
13.
Can this happen to my dog again?
Recurrence
of symptoms after recovery is related to the type of therapy used and the
activity level and weight of the dog (lifestyle changes). With medical
therapy the chance of having a recurrence of back pain, weakness and/or
paralysis can be as high as 34%. This can be the result of more disk
material entering the canal from the original herniated disk site or it
may be a new problem at another disk space. Limiting activity after
recovery is thought to prevent a recurrence of the problem. This is
because susceptible breeds of dogs have multiple degenerative disks in their
lower back that are at risk for herniation.
With
surgery (hemilaminectomy and removal of herniated disk material from the spinal
canal) there is still a chance of disk herniation at another site in the lower
back. This chance can be minimized (reportedly to as low as 4-10%
recurrence rate) at the time of surgery when the surgeon fenestrates the
offending disk space and the 2 adjacent disk spaces. Because all
susceptible thoracolumbar disk spaces cannot be addressed surgically, lifestyle
changes and weight control are recommended in surgery patients also.
14.
How does IVDD in large breed dogs differ from that in small chondrodystrophic
breeds?
Large
breed dogs rarely have disk extrusions (pushing of the nucleus through the
annulus and into the spinal canal) that are common in small chondrodystrophic
breeds. Disk extrusions in small breeds are classified as Hansen Type 1
Disk Disease. Large breed dogs more frequently have a build up of scar
tissue over the outer layer of the disk (the annulus) that pushes up on the
spinal cord and gradually causes pain and weakness. This condition is
classified as Hansen Type 2 Disk Disease. Hansen Type 2 Disk Disease
causes slowly progressive neurologic impairment. These dogs are usually older
and may not be as painful as the small breeds with Type 1 disease.
Surgical therapy for Type 2 disease may not be as successful for large
breed dogs and recovery commonly takes longer than for small dogs. Hansen
Type 2 Disk Disease must be differentiated from other causes of neurologic
dysfunction that also affects principally large breed dogs such as Degenerative
Myelopathy, Diskospondylitis or Fibrocartilaginous Emboli. Myelography
can be used to help distinguish Hansen Type 2 Disk Disease from these other
similarly appearing neurologic conditions of large breed dogs but MRI or CT are
generally preferred because these exams are noninvasive and are less likely to
make the dog’s condition worse.
15.
How does cervical (neck region) IVDD differ from thoracolumbar (lower back
region) IVDD?
Cervical
disk disease accounts for approximately 15% of the Type 1 IVDD cases.
Thoracolumbar disk herniation is responsible for the other 85% of cases
in small dogs. There is more space in the cervical spinal canal around
the spinal cord than there is in the thoracolumbar canal. This
characteristic means that cervical disk herniation only very rarely causes compression
of the spinal cord that is severe enough to result in neurologic deficits.
Pain is the hallmark of cervical IVDD. Conservative medical therapy
for IVDD is similar to that used for thoracolumbar IVDD, but may not be as
successful. Unremitting pain is the primary indication for surgery in cervical
IVDD. Cervical IVDD like thoracolumbar IVDD is also divided into Hansen
Types 1 & 2 corresponding to small chondrodystrophic breeds with disk
extrusions (Type 1) and large breed dogs who have scarred annulus fibrosis
(Type 2 disease and Wobblers Disease). Surgical therapy for small
chondrodystrophic breeds affected with cervical IVDD consists of ventral
decompression and disk removal through a ventral slot. In small
chondrodystrophic breeds, fenestration of the remaining cervical discs is
thought to help prevent future episodes of cervical IVDD.
Intervertebral
Disc Disease Medical vs. Surgical Therapy
|
Grade
|
Symptoms
|
Success Medical
|
Success Surgery
|
|
1
|
Pain
|
~ 100%
|
97%
|
|
2
|
Ataxia
|
90-95%
|
95%
|
|
3
|
Paralysis
|
80-90%
|
95%
|
|
4
|
Unable to Urinate
|
50-80%
|
90-95%
|
|
5
|
Loss of Deep Pain
|
15%
|
~50% within 12 hours
|
Recurrence
Rate 33-50%
4-10%
Medical
therapy =
Administer pain relievers +/- muscle relaxants, 3-6 weeks of Strict Cage
Confinement
Surgical
therapy =
General anesthesia followed by myelogram and decompressive surgery with
fenestration of high-risk disc spaces. Expect unassisted walking within 10-14
days.